ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Developing systemic & inhaled antibiotics for lung infections
FDA workshop: Insights on inhaled antifungals and antibacterials
Modeling the value of an effective antibiotic — Megiddo et al.
NIAID workshop: What is a robust PK-PD package?
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
The 37,000-year view: Infections in Eurasia
Melinta goes bankrupt / Never let a good crisis go to waste
Novel Biology, Novel Utility, & the Illusion of Skill: What to develop? What to reward?
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet